Rituximab is an anticancer medicine that is used for the treatment of Blood Cancers.
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Mabthera 100mg/10ml Solution for Infusion, which contains Rituximab and is used in the treatment of various conditions, including blood cancer, lymphoma, rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris. Here's a summary:
Mabthera 100mg/10ml Solution for Infusion is used to treat:
It is administered by a healthcare professional, typically an oncologist, through intravenous infusion into the vein.
Before receiving Mabthera 100mg/10ml Solution for Infusion, inform your doctor if you have heart problems, a history of hepatitis B infection, or any other mild infections. It is not recommended for use in pregnant or breastfeeding women. Both men and women receiving this Solution for Infusion should use suitable contraceptive methods to avoid pregnancy during the therapy.
Avoid consumption of alcohol while receiving Mabthera 100mg/10ml Solution for Infusion as it may make you feel drowsier.
Mabthera 100mg/10ml Solution for Infusion is generally not recommended for use in pregnant women. Consult your doctor before receiving it. Women of childbearing potential must use a suitable contraceptive to avoid pregnancy while undergoing therapy with Mabthera 100mg/10ml Solution for Infusion and until 12 months after stopping the therapy. If you accidentally become pregnant while receiving Mabthera 100mg/10ml Solution for Infusion, inform your doctor immediately.
Contraindicated for use in breastfeeding women. Consult your doctor before receiving it.
Do not drive or operate any machines if your ability is affected by Mabthera 100mg/10ml Solution for Infusion.
Mabthera 100mg/10ml Solution for Infusion is likely safe to use in patients with kidney disease. Limited data available suggests that dose adjustment may not be needed in these patients. However, it's crucial to consult your doctor for personalized advice and monitoring.
Consult your doctor regarding the use of Mabthera 100mg/10ml Solution for Infusion in patients with liver disease. Limited information is available on its use in patients with liver disease. Use of Mabthera 100mg/10ml Solution for Infusion is not recommended in patients with active liver disease or those who have had viral hepatitis, as it can reactivate the infection.
Rituximab is used to treat:
Rituximab is a monoclonal antibody, that works by targeting the unwanted activity of blood cells. This helps in managing cancer.
Hepatitis B virus reactivation, fever, pruritus, rash, dyspnoea, bronchospasm, angioedema, hypotension, flushing, asthenia, headache, rhinitis, thrombocytopenia, leukopenia, anemia, abdominal pain, intestinal obstruction, puncture, exacerbation of heart failure and angina, reversible interstitial pneumonia, interstitial fibrosis, decreased immunoglobulin levels.
Non-Hodgkin's Lymphoma (NHL):
Chronic Lymphocytic Leukemia (CLL):
Rheumatoid Arthritis (RA):
Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA):
Rituximab is a monoclonal antibody targeting CD20 antigen, inducing complement-dependent B-cell toxicity and antibody-dependent cytotoxicity.
Before receiving Mabthera 100mg/10ml Solution for Infusion, inform your doctor if you are taking any of the following medicines:
Medicines used to treat high blood pressure:
Medicines that can suppress immune functions:
Other anticancer medicines:
Pregnancy group C. Use only if the potential benefit to the fetus outweighs the risks.
Extensive tumor burden, pulmonary insufficiency or tumor infiltration, history of cardiac disease, pregnancy.
Store between 2-8°C.
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