Mabthera 100mg/10ml Solution for Infusion | Rituximab | ePharma
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Mabthera 100mg/10ml Solution for Infusion

Generic: Rituximab

Type: Infusion

Pack Size: 100ml

Rituximab is an anticancer medicine that is used for the treatment of Blood Cancers.


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Discount Price: ৳ 12350
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✅ Description:

Mabthera 100mg/10ml Solution for Infusion, which contains Rituximab and is used in the treatment of various conditions, including blood cancer, lymphoma, rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris. Here's a summary:

Mabthera 100mg/10ml Solution for Infusion is used to treat:

  • Blood cancer (leukemia)
  • Lymph cancer (lymphoma)
  • Autoimmune diseases such as rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris.

It is administered by a healthcare professional, typically an oncologist, through intravenous infusion into the vein.

Before receiving Mabthera 100mg/10ml Solution for Infusion, inform your doctor if you have heart problems, a history of hepatitis B infection, or any other mild infections. It is not recommended for use in pregnant or breastfeeding women. Both men and women receiving this Solution for Infusion should use suitable contraceptive methods to avoid pregnancy during the therapy.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while receiving Mabthera 100mg/10ml Solution for Infusion as it may make you feel drowsier.


Pregnancy
CONSULT YOUR DOCTOR

Mabthera 100mg/10ml Solution for Infusion is generally not recommended for use in pregnant women. Consult your doctor before receiving it. Women of childbearing potential must use a suitable contraceptive to avoid pregnancy while undergoing therapy with Mabthera 100mg/10ml Solution for Infusion and until 12 months after stopping the therapy. If you accidentally become pregnant while receiving Mabthera 100mg/10ml Solution for Infusion, inform your doctor immediately.


Breastfeeding
CONSULT YOUR DOCTOR

Contraindicated for use in breastfeeding women. Consult your doctor before receiving it.


Driving
CAUTION

Do not drive or operate any machines if your ability is affected by Mabthera 100mg/10ml Solution for Infusion.


Kidney
CONSULT YOUR DOCTOR

Mabthera 100mg/10ml Solution for Infusion is likely safe to use in patients with kidney disease. Limited data available suggests that dose adjustment may not be needed in these patients. However, it's crucial to consult your doctor for personalized advice and monitoring.


Liver
CONSULT YOUR DOCTOR

Consult your doctor regarding the use of Mabthera 100mg/10ml Solution for Infusion in patients with liver disease. Limited information is available on its use in patients with liver disease. Use of Mabthera 100mg/10ml Solution for Infusion is not recommended in patients with active liver disease or those who have had viral hepatitis, as it can reactivate the infection.

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✔️ Uses of Mabthera 100mg/10ml Injection

Rituximab is used to treat:

  • Blood cancer (Chronic lymphocytic leukemia)
  • Lymph cancer (Non-Hodgkin’s Lymphoma)
  • Rheumatoid arthritis (joint pain and inflammation)
  • Granulomatosis with polyangiitis or microscopic polyangiitis (inflammation of blood vessels)
  • Pemphigus vulgaris (severe skin blistering and peeling especially on the mouth, nose, throat, eyes, and genitals)
✔️ How does Mabthera 100mg/10ml Injection work?

Rituximab is a monoclonal antibody, that works by targeting the unwanted activity of blood cells. This helps in managing cancer.

✔️ Side Effects of Mabthera 100mg/10ml Injection

Hepatitis B virus reactivation, fever, pruritus, rash, dyspnoea, bronchospasm, angioedema, hypotension, flushing, asthenia, headache, rhinitis, thrombocytopenia, leukopenia, anemia, abdominal pain, intestinal obstruction, puncture, exacerbation of heart failure and angina, reversible interstitial pneumonia, interstitial fibrosis, decreased immunoglobulin levels.

✔️ Quick Suggestions:
  • Mabthera 100mg/10ml Solution is administered as an intravenous infusion by your doctor or nurse.
  • You may receive painkillers, antihistamines, and possibly steroids before the drip to help prevent infusion reactions.
  • Blood tests may be conducted to check for hepatitis B before treatment and to monitor your blood cells during treatment with this medicine.
  • Be vigilant and inform your doctor immediately if you notice any signs of infection, such as fever, sore throat, or rash.
  • Inform your doctor if you are pregnant, planning to conceive, or breastfeeding.
  • Inform your doctor if you have any heart rhythm problems.
  • If you are planning to have surgery, it's important to communicate this to your doctor.
  • Let your doctor know if you plan to get any vaccinations.
✔️ Indications of Mabthera 100mg/10ml Solution for Infusion

Non-Hodgkin's Lymphoma (NHL):

  • Recurrent or refractory NHL, low-grade or cystic, CD20 positive, monotherapy B-cell LNH cystic form (not previously treated).
  • In combination with first-line chemotherapy for CD20-positive B-cell LNH.
  • In patients with a complete or partial response to Rituxan in combination with chemotherapy, as maintenance monotherapy.
  • Monotherapy after first-line chemotherapy (CVP) for low-level, CD20-positive, NHL B-cell (no progression, including stable disease).
  • Diffuse large B-cell NHL, untreated CD20-positive, prior combination with CHOP or another anthracycline-based chemotherapy regimen.

Chronic Lymphocytic Leukemia (CLL):

  • In combination with fludarabine and cyclophosphamide (FC) for untreated and previously treated CD20-positive CLL.

Rheumatoid Arthritis (RA):

  • In combination with methotrexate for adult patients with moderate to severe active rheumatoid arthritis who had an inadequate response to one or more TNF blockers.

Granulomatosis with Polyangiitis (GPA) and Microscopic Polyangiitis (MPA):

  • In combination with glucocorticoids for adult patients with GPA and MPA.
✔️ Pharmacology

Rituximab is a monoclonal antibody targeting CD20 antigen, inducing complement-dependent B-cell toxicity and antibody-dependent cytotoxicity.

✔️ Dosage & Administration of Mabthera 100mg/10ml Solution for Infusion
  • Intravenous (Adult):
    • Non-Hodgkin's Lymphoma: Various dosages based on the type and stage of lymphoma.
    • Chronic Lymphocytic Leukemia: 375 mg/m2 on the day before chemotherapy in cycle 1, followed by 500 mg/m2 on day 1 of cycles 2-6.
    • Rheumatoid Arthritis: Two 1g IV infusion doses separated by 2 weeks, in combination with methotrexate.
✔️ Interaction

Before receiving Mabthera 100mg/10ml Solution for Infusion, inform your doctor if you are taking any of the following medicines:

Medicines used to treat high blood pressure:

  • Atenolol
  • Propranolol
  • Amlodipine
  • Enalapril
  • Olmesartan
  • Losartan

Medicines that can suppress immune functions:

  • Ciclosporin
  • Tacrolimus

Other anticancer medicines:

  • Trastuzumab
  • Bevacizumab
  • Alemtuzumab
  • Cetuximab
✔️ Contraindications
  • Hypersensitivity to murine proteins.
  • Patients with active, severe infections.
  • Severely immunocompromised state.
  • Concomitant use with live viral vaccines.
  • Lactation.
✔️ Pregnancy & Lactation

Pregnancy group C. Use only if the potential benefit to the fetus outweighs the risks.

✔️ Precautions & Warnings

Extensive tumor burden, pulmonary insufficiency or tumor infiltration, history of cardiac disease, pregnancy.

✔️ Storage Conditions

Store between 2-8°C.

Frequently Asked Questions (FAQ)

The cure rate of cancer depends upon the severity of the disease. However, Mabthera 100mg/10ml Solution for Infusion acts by preventing the abnormal growth and multiplication of cancer cells in the body, which may help in curing cancer completely.

Mabthera 100mg/10ml Solution for Infusionn is a anticancer medicine containing rituximab as its active medicine. Rituximab is a monoclonal antibody, it works by targetting the unwanted activity of blood cells. This helps in managing cancer.

Mabthera 100mg/10ml Solution for Infusion should be used in children and adolescents (aged below 18 years) only if prescribed by the physician. Therefore, consult your doctor for advice before receiving it.

Yes

The initial response to this medicine can be observed within 7 to 14 days of administration.

The effect of Mabthera 100mg/10ml Solution for Infusion can be detected for up to 6 months after completion of the treatment.
Ratings & Reviews

No review

Check our pricing section for Mabthera 100mg/10ml Solution for Infusion price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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